. Author manuscript; available in PMC: 2011 Jan 4.

Published in final edited form as: Dev Dyn. 2009 Oct;238(10):2459–2470. doi: 10.1002/dvdy.22062

Table 4. Full-length Pitx2c^L41A is able to randomize heart looping when overexpressed on the right side of HH stage 4 chick embryos.

Injected Retrovirus (on right side)	% Abnormal (Leftward) Heart Looping
RCAS (empty vector)	8% (n= 3/40)
Wild type Pitx2c	33% (n=19/58) χ² = 8.68 (p<0.005)
Pitx2c^L41A	25% (n=15/59) χ² vs. RCAS = 5.15 (p<0.05) χ² vs. WT = 0.76 (N.S.)

Table 4. Full-length Pitx2cL41A is able to randomize heart looping when overexpressed on the right side of HH stage 4 chick embryos.