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. 2010 Dec 21;7(12):e1000384. doi: 10.1371/journal.pmed.1000384

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Boulware et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The data are based on a weighed predictive biomarker score composed of pre-ART serum levels of seven biomarkers—IL-4, IL-17, G-CSF, GM-CSF, CCL2 (MCP-1), TNF-α, and VEGF—calculated as follows. Probability of IRIS = where:
Probability risk is scored from 0 to 1.0 with the categorical classification being defined for low risk (0–0.40), moderate risk (0.41–0.60), and high risk (0.61–1.0). The performance as quantified by the AUC is 0.82 for correct prediction (i.e. C-statistic).

Inline graphic — The data are based on a weighed predictive biomarker score composed of pre-ART serum levels of seven biomarkers—IL-4, IL-17, G-CSF, GM-CSF, CCL2 (MCP-1), TNF-α, and VEGF—calculated as follows. Probability of IRIS = where:
Probability risk is scored from 0 to 1.0 with the categorical classification being defined for low risk (0–0.40), moderate risk (0.41–0.60), and high risk (0.61–1.0). The performance as quantified by the AUC is 0.82 for correct prediction (i.e. C-statistic).