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. 2011 Feb 1;138(3):507–518. doi: 10.1242/dev.060939

Fig. 3.

Fig. 3.

bicd-1(ok2731) animals phenocopy the bicd-1 RNAi enhanced-branching defect. (A) Genetic position of bicd-1 on chromosome IV and its exon-intron structure, with the positions of the ok2731 and tm3421 mutations indicated. (B,C) Schematics of individual PVD dendrite trees present in wild-type (B) and bicd-1(ok2731) or bicd-1 RNAi-treated (C) animals. (D,E) otIs138 animals fed bicd-1 dsRNA exhibit an enhanced-branching phenotype posterior to the PVD cell body (D). bicd-1(ok2731) animals phenocopy the bicd-1 RNAi enhanced-branching phenotype (E). Purple arrowheads indicate ectopic tertiary dendrites. Asterisks indicate the spermatheca. Anteroposterior orientation is indicated by the white double-headed arrow. (F) Quantification of the enhanced-branching phenotype exhibited by otIs138 young adult animals subjected to bicd-1 RNAi. (G) The PVD enhanced-branching phenotype is first apparent at the young adult stage. n, number of secondary dendrites scored in F and G. Error bars represent s.e.m. ***P<0.001 determined by unpaired Student's t-test with Bonferroni adjustment. n.s., not significant. Scale bars: 10 μm.