Table 3.
Diagnosis to listing | Diagnosis to death | Listing to transplant | Listing to death | |||||
---|---|---|---|---|---|---|---|---|
Variable | Beta | P-value | Beta | P-value | Beta | P-value | Beta | P-value |
Age | ||||||||
18–39 | <ref> | <ref> | ||||||
40–64 | 0.1018 | 8.70E − 02 | 0.5747 | 0.00E + 00 | 0.1388 | 0.11 | 0.01719 | 0.89 |
≥65 | −2.181 | 0.00E + 00 | 0.981 | 0.00E + 00 | −0.0751 | 0.66 | 0.3803 | 0.076 |
| ||||||||
Gender | ||||||||
Male | <ref> | <ref> | ||||||
Female | 0.05282 | 3.10E − 01 | −0.2175 | 0.00E + 00 | −0.2165 | 0.0021 | 0.04415 | 0.69 |
| ||||||||
Race/ethnicity | ||||||||
White | <ref> | <ref> | ||||||
Black | −0.7324 | 5.90E − 12 | 4.14E − 02 | 1.70E − 01 | −0.115 | 0.44 | 0.5058 | 7.10E − 03 |
Hispanic/Asian/other | 0.1405 | 2.10E − 01 | −2.90E − 01 | 1.40E − 08 | −0.2502 | 0.11 | −0.01805 | 9.40E − 01 |
Unknown | 0.1394 | 7.30E − 02 | 1.35E − 02 | 6.40E − 01 | −0.2215 | 0.045 | −0.07929 | 6.50E − 01 |
| ||||||||
Insurance status | ||||||||
Medicare only | <ref> | <ref> | ||||||
Medicare plus Medicaid | −0.411 | 4.30E − 02 | 0.1222 | 1.10E − 03 | −0.2997 | 0.25 | −0.2164 | 0.54 |
Medicare plus commercial | −0.05088 | 7.30E − 01 | −0.004856 | 8.40E − 01 | −0.1507 | 0.41 | 0.05829 | 0.8 |
Medicaid only | −0.1287 | 3.40E − 01 | 0.08097 | 2.30E − 02 | −0.1433 | 0.37 | 0.03886 | 0.87 |
Commercial only | 0.6716 | 2.60E − 08 | −0.267 | 0.00E + 00 | −0.0757 | 0.6 | −0.1517 | 0.49 |
Uninsured (including self-pay) | −0.06924 | 7.00E − 01 | −0.1487 | 1.80E − 02 | −0.1072 | 0.61 | 0.06899 | 0.82 |
| ||||||||
Severity of illness at diagnosis | ||||||||
None | <ref> | <ref> | ||||||
Minimal | 0.206 | 2.00E − 02 | 0.7547 | 0.00E + 00 | 0.02335 | 0.85 | −0.07078 | 0.72 |
Moderate | 0.9264 | 0.00E + 00 | 1.334 | 0.00E + 00 | 0.02553 | 0.82 | 0.002209 | 0.99 |
Severe | 0.9892 | 0.00E + 00 | 2.022 | 0.00E + 00 | 0.01008 | 0.93 | 0.1598 | 0.41 |
Maximal | 0.2154 | 2.10E − 01 | 2.724 | 0.00E + 00 | −0.2741 | 0.36 | 1.031 | 0.0012 |
| ||||||||
Liver diagnoses (five groups) | ||||||||
(1) (PBC, PSC, ALD, and autoimmune) | <ref> | <ref> | ||||||
(2) (Viral hepatitis) | −0.7455 | 1.10E − 02 | −0.2798 | 5.60E − 07 | 0.06082 | 0.59 | 0.1554 | 0.38 |
(3) (Acute liver failure) | −1.111 | 6.30E − 03 | 0.3353 | 4.50E − 07 | −0.3713 | 0.04 | −0.06777 | 0.79 |
(4) (Cancer) | −1.959 | 6.00E − 02 | 0.6301 | 0.00E + 00 | −0.2334 | 0.42 | 0.1335 | 0.77 |
(5) (Metabolic disease, other) | −1.859 | 1.30E − 08 | −0.04497 | 1.40E − 01 | −0.2278 | 0.094 | 0.1449 | 0.49 |
| ||||||||
Pennsylvania transplant center | ||||||||
No | N/A | <ref> | ||||||
Yes | 0.3121 | 0.0021 | 0.5502 | 0.0011 | ||||
| ||||||||
INTERACTION TERMS | ||||||||
Diagnosis group × gender | ||||||||
2 × Female | −0.1599 | 1.80E − 01 | 0.006272 | 8.60E − 01 | 0.05301 | 0.77 | 0.2293 | 0.38 |
3 × Female | 0.459 | 1.80E − 03 | 0.05483 | 2.40E − 01 | 0.3382 | 0.19 | 0.3079 | 0.32 |
4 × Female | −0.9512 | 8.50E − 03 | −0.1406 | 5.60E − 03 | 1.218 | 0.035 | −0.2633 | 0.77 |
5 × Female | −0.2384 | 6.20E − 02 | 0.004479 | 8.40E − 01 | 0.07122 | 0.73 | −0.03655 | 0.9 |
| ||||||||
Diagnosis group × race/ethnicity | ||||||||
2 × Black | −0.03861 | 8.30E − 01 | 0.1662 | 2.80E − 04 | −0.2849 | 0.31 | −0.2854 | 0.41 |
3 × Black | 0.243 | 3.30E − 01 | −0.06367 | 3.20E − 01 | −0.2003 | 0.64 | −0.4171 | 0.41 |
4 × Black | 0.5954 | 3.00E − 01 | 0.05434 | 5.60E − 01 | 0.361 | 0.73 | −0.2571 | 0.8 |
5 × Black | 0.5146 | 2.80E − 02 | 0.08273 | 4.30E − 02 | −0.3152 | 0.45 | −0.2944 | 0.53 |
2 × Hispanic/Asian/other | −0.06936 | 7.40E − 01 | 0.1438 | 8.20E − 02 | 0.2924 | 0.34 | −0.6491 | 0.23 |
3 × Hispanic/Asian/other | 0.3302 | 3.00E − 01 | 0.121 | 3.50E − 01 | 0.301 | 0.6 | 0.9397 | 0.071 |
4 × Hispanic/Asian/other | 0.5255 | 2.50E − 01 | −0.2266 | 9.30E − 02 | 0.7187 | 0.12 | −8.938 | 0 |
5 × Hispanic/Asian/other | −0.009698 | 9.80E − 01 | 0.0801 | 2.80E − 01 | −0.9032 | 0.26 | 1.197 | 0.028 |
2 × Unknown | −0.3849 | 5.30E − 02 | −0.01653 | 8.00E − 01 | 0.3819 | 0.11 | −0.8792 | 0.16 |
3 × Unknown | 0.2203 | 3.10E − 01 | 0.0593 | 4.30E − 01 | −0.8466 | 0.092 | 1.048 | 0.01 |
4 × Unknown | −0.01568 | 9.70E − 01 | −0.08379 | 3.30E − 01 | −0.1711 | 0.8 | −8.964 | 0 |
5 × Unknown | −0.07788 | 7.10E − 01 | 0.01727 | 6.50E − 01 | 0.5868 | 0.069 | −0.2218 | 0.66 |
| ||||||||
Diagnosis group × insurance status | ||||||||
2 × Medicare plus Medicaid | 0.01518 | 9.70E − 01 | 0.0759 | 3.30E − 01 | ||||
3 × Medicare plus Medicaid | −0.2036 | 7.80E − 01 | −0.08408 | 4.70E − 01 | ||||
4 × Medicare plus Medicaid | −3.869 | 1.70E − 04 | −0.1627 | 2.40E − 01 | ||||
5 × Medicare plus Medicaid | −0.004049 | 9.90E − 01 | 0.005655 | 9.10E − 01 | ||||
2 × Medicare plus commercial | 0.1845 | 6.20E − 01 | 0.004062 | 9.50E − 01 | ||||
3 × Medicare plus commercial | 0.4838 | 3.20E − 01 | −0.1051 | 1.70E − 01 | N/A | |||
4 × Medicare plus commercial | 0.6797 | 5.50E − 01 | −0.2542 | 7.90E − 04 | ||||
5 × Medicare plus commercial | −0.1228 | 7.50E − 01 | −0.04907 | 1.30E − 01 | ||||
2 × Medicaid only | −0.3384 | 2.90E − 01 | −0.1179 | 6.50E − 02 | ||||
3 × Medicaid only | 0.1897 | 6.60E − 01 | −0.6395 | 6.20E − 15 | ||||
4 × Medicaid only | 0.5077 | 6.70E − 01 | 0.001579 | 9.90E − 01 | ||||
5 × Medicaid only | 0.2893 | 4.30E − 01 | −0.1224 | 1.20E − 02 | ||||
2 × Commercial only | −0.2162 | 4.70E − 01 | −0.2046 | 9.00E − 04 | ||||
3 × Commercial only | −0.2264 | 5.80E − 01 | −0.274 | 1.90E − 04 | ||||
4 × Commercial only | 0.6286 | 5.40E − 01 | −0.1069 | 2.00E − 01 | ||||
5 × Commercial only | −0.2812 | 4.00E − 01 | −0.09617 | 9.70E − 03 | ||||
2 × Uninsured | −0.2524 | 5.40E − 01 | −0.5278 | 9.30E − 06 | ||||
3 × Uninsured | −0.7369 | 2.10E − 01 | −0.5542 | 1.10E − 05 | ||||
4 × Uninsured | 1.552 | 2.00E − 01 | −0.5514 | 1.50E − 02 | ||||
5 × Uninsured | 0.4768 | 3.10E − 01 | −0.2448 | 1.10E − 02 |
Abbreviations: PBC-primary biliary cirrhosis; PSC-primary sclerosing cholangitis; ALD-alcoholic liver disease.