Table 3.
Within-Subject Variability for 2-h Oral Glucose Tolerance Test Glucose and Breath-Derived Tests
| |
Lean |
Obese |
T2DM |
All subjects |
||||
|---|---|---|---|---|---|---|---|---|
| Test | CV | RMS-CV | CV | RMS-CV | CV | RMS-CV | CV | RMS-CV |
| 2-h OGTT (mg/dL) | 16.6 ± 8.2% | 18.3 | 10.3 ± 6% | 11.7 | 10.9 ± 5.2% | 11.9 | 13 ± 7.1%bd | 14.8 |
| δ180 (‰) | 5.3 ± 2.0% | 5.6 | 7.6 ± 5.2% | 8.9 | 10 ± 3.2% | 10.4 | 7.4 ± 3.9%acd | 8.3 |
| AUC180 (‰ × min) | 6.5 ± 3.6% | 7.3 | 9.2 ± 8.9% | 12.3 | 13.5 ± 4.3% | 14.1 | 9.4 ± 6.3%b | 11.2 |
| Lox/Gox | 6.5 ± 3.5% | 7.3 | 8.7 ± 8.3% | 11.6 | 13.3 ± 4.5% | 14 | 9.2 ± 6%ab | 11 |
Data are mean ± SD values.
Comparisons of coefficient of variationvalues across tests are presented in the second to last column for all subjects; superscripts indicate P < 0.05 comparing against a2-h oral glucose tolerance test (OGTT) blood glucose, bchange at 180 min (δ180), carea under the curve for enrichment to 180 min (AUC180), or dratio of lipid oxidation to glucose oxidation (Lox/Gox).
CV, coefficient of variation; RMS-CV, root mean squared CV; T2DM, type 2 diabetes mellitus.