Table 2. Summary of comparisons of cone cell quantifications in treated and untreated rd12, Rpe65^−/−::Rho^−/− or wild type retinas as measured by PNA, MWL or SWL cone opsin immunostaining.

Cone photoreceptors were counted in the central (C), dorsal temporal (DT), ventral temporal (VT), dorsal nasal (DN) and ventral nasal (VN) quadrants of each retina. Values were calculated and averaged in five areas (500 μm²) per quadrant. A standard t-test was used to calculate p-values between desired samples. Significant difference was defined as a p value < 0.05.

	C	DT	VT	DN	VN
Figure 1
P14 WT vs. P14 rd12 (PNA)
P14 WT vs. 5 weeks rd12 (PNA)	*		*	*	*
P14 WT vs. 5 months rd12 (PNA)	*		*	*	*
P14 rd12 vs. 5 weeks rd12 (PNA)	*		*	*	*
P14 rd12 vs. 5 months rd12 (PNA)	*		*	*	*
5 weeks rd12 vs. 5 months rd12 (PNA)			*	*
Figure 4
P14 WT vs. P14-treated rd12 (PNA)
P14 WT vs. P35-treated rd12 (PNA)	*		*	*	*
P14 WT vs. P14-treated rd12 (MWL)	*		*		*
P14 WT vs. P14-treated rd12 (SWL)	*				*
P14 WT vs. P35-treated rd12 (MWL)	*		*		*
P14 WT vs. P35-treated rd12 (SWL)	*	*	*	*	*
P14-treated rd12 vs. P35-treated rd12 (PNA)	*		*	*	*
P14-treated rd12 vs. P35-treated rd12 (MWL)					*
P14-treated rd12 vs. P35-treated rd12 (SWL)	*	*	*	*	*
P35-treated rd12 vs. 5 months rd12 (PNA)
Figures 5 and 7
P14 DKO vs. P14 WT (PNA)
P14 DKO vs. 5 weeks DKO (PNA)	*		*	*	*
P14 WT vs. 5 weeks DKO (PNA)	*		*	*	*
P14-treated DKO vs. P14 WT (PNA)
P14-treated DKO vs. P14 DKO (PNA)
P14-treated DKO vs. P14 WT (MWL)				*
P14-treated DKO vs. P14 WT (SWL)	*				*