Table 3.
Comparison of areas under the ROC curves (95% CI) for potential markers of insulin resistance (HOMA-IR§ > 2.5) of subjects categorized by body mass index
| AUC (95% CI) | ||||||
|---|---|---|---|---|---|---|
| Total | Non-obese | Overweight | ||||
| Body mass index Characteristics |
All N = 1,393 |
P-value |
<25.0 kg/m2 N = 1,042 |
P-value |
>25.0 kg/m2 N = 351 |
P-value |
| Triglycerides (mg/dL) | 0.69 (0.45-0.73) | <0.001 | 0.66 (0.59-0.72) | <0.001 | 0.64 (0.58-0.71) | <0.001 |
| HDL cholesterol (mg/dL) | 0.33 (0.28-0.37) | <0.001 | 0.31 (0.24-0.38) | <0.001 | 0.41 (0.35-0.48) | 0.009 |
| LDL cholesterol (mg/dL) | 0.61 (0.56-0.65) | <0.001 | 0.65 (0.58-0.72) | <0.001 | 0.54 (0.48-0.61) | 0.188 |
| Triglycerides/HDL cholesterol ratio | 0.70 (0.66-0.75) | <0.001 | 0.69 (0.62-0.75) | <0.001 | 0.64 (0.57-0.70) | <0.001 |
| Non-HDL cholesterol (mg/dL) | 0.66 (0.61-0.70) | <0.001 | 0.69 (0.62-0.75) | <0.001 | 0.59 (0.52-0.65) | 0.011 |
| LDL-cholesterol/HDL-cholesterol ratio | 0.69 (0.65-0.73) | <0.001 | 0.74 (0.66-0.80) | <0.001 | 0.58 (0.51-0.65) | 0.021 |
ROC, receiver operating characteristics; HOMA-IR, homeostasis of minimal assessment of insulin resistance; CI, confidence interval; AUC, area under ROC curve; HDL, high-density lipoprotein; LDL, low-density lipoprotein. §HOMA-IR was calculated using the following formula; {fasting blood glucose (mg/dL) X immuno-reactive insulin (mU/mL)}/405.