Skip to main content
. 2011 Jan 4;5(1):e933. doi: 10.1371/journal.pntd.0000933

Figure 2. Delay in footpad swelling in mice receiving different drug regimens.

Figure 2

Kaplan-Meier curve depicting the percentage of mice free of footpad swelling during 39 weeks of follow-up after infection. The dotted vertical line shows the expected delay in time to swelling for a bacteriostatic drug. The dotted horizontal line indicates footpad swelling in 50% of mice. A) Single drug regimens: Effect of single drugs compared to the standard regimen STR+RIF. Rifapentine alone prevented relapse as well as the standard STR+RIF regimen and better than any other single drug. B) Combination drug regimens with a rifamycin±CLR: Effect of adding CLR to either RIF or RPT. CLR = clarithromycin; RIF = rifampin; RPT = rifapentine, STR = streptomycin.