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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Biol Psychiatry. 2010 Nov 20;69(3):275–281. doi: 10.1016/j.biopsych.2010.09.032

Figure 5. Inactive lever pressing during mirtazapine.

Figure 5

Shown are data from the rats that completed the cue reactivity (n=15) and cue-induced reinstatement (n=37) paradigms. A. Cue reactivity. A two-way rmANOVA revealed no Treatment effect (F(3,44)=2.29), a significant Time effect (F(3,132)=13.46) with no Treatment x Time interaction (F(9,132)=1.92); three statistical outliers excluded from analysis. B. Cue-induced reinstatement. A two-way rmANOVA revealed no Treatment effect (F(3,44)=2.29) on inactive lever pressing. A significant Time effect was demonstrated (F(3,132)=13.46) with no Treatment x Time interaction (F(9,132)=1.92). Newman-Keuls post-hoc analysis indicated a significant decrease comparing 5.0mg/kg mirtazapine vs. vehicle in the first 15min of testing (*p<0.05); one statistical outlier removed from vehicle and 0.5mg/kg mirtazapine pretreated groups.