Skip to main content
. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Biol Psychiatry. 2010 Nov 20;69(3):275–281. doi: 10.1016/j.biopsych.2010.09.032

Figure 6. Rotorod evaluations of the motor effects of mirtazapine.

Figure 6

Sixteen rats, separate from those used for self-administration, were evaluate for rotorod performance. Two-way rmANOVA revealed a Treatment effect (F(4,75)=9.91), Time effect (F(4,300)=21.74), and Treatment x Time interaction (F(16,300)=2.44). Mirtazapine had no effect on rotorod performance at any dose tested. The positive control, 10 mg/kg ip pentobarbital significantly impairment of rotorod performance across all time points tested (**p<0.01; Newman-Keuls post hoc).