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. 2010 Dec;277(23):4837–4848. doi: 10.1111/j.1742-4658.2010.07900.x

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Journal compilation © 2010 Federation of European Biochemical Societies

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Fig. 3 — Alternative tumour suppressor mechanisms of PI3K-III. Three alternative (hypothetic) tumour suppressor mechanisms downstream of PtdIns3P formation are shown. The relative importance of these mechanisms in the tumour suppressor activity of PI3K-III subunits remains to be established.