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. Author manuscript; available in PMC: 2011 Jan 5.
Published in final edited form as: Nutr Cancer. 2006;54(1):47–57. doi: 10.1207/s15327914nc5401_6

Figure 4.

Figure 4

Effect of isolated components known to be present in black raspberry (BRBs) on N-nitrosomethylbenzylamine (NMBA) metabolism in esophageal explant cultures. Esophagi from control rats were excised and aseptically removed to prepare explant cultures. The cultures were treated with the ethanol extract of BRBs (100 µg/ml), ellagic acid (100 µM), cyaniding-3-glucoside (100 µM), cyaniding-3-rutinoside (100 µM), or phenylethylisothiocyanate (100 µM) and incubated for 30 min. Other conditions are as explained in Fig. 2. Medium was analyzed for unmetabolized NMBA (filled bars) and benzoic acid formation (empty bars). Each bar represents mean values ± SD(n = 9 rats) from three independent experiments. *Statistically significant difference from control group (P < 0.05).