Table 4.
Gene | SNP | Families | % failed | Complete families |
Allele 2 transmitted |
Allele 2 not transmitted |
% transmission | p Value |
---|---|---|---|---|---|---|---|---|
Principal phenotypes | ||||||||
SLC22A5 | rs14701 | 658 | 5.6 | 554 | 139 | 129 | 51.9 | 0.54 |
IL13 | rs1800925 | 659 | 4.1 | 582 | 162 | 177 | 47.8 | 0.42 |
IL13 | rs1295686 | 660 | 3.3 | 598 | 197 | 177 | 52.7 | 0.30 |
IL13 | rs20541 | 673 | 2.4 | 625 | 200 | 191 | 51.2 | 0.65 |
IL4 | rs2243250 | 660 | 2.7 | 604 | 154 | 132 | 53.8 | 0.19 |
IL4 | rs2070874 | 658 | 4.8 | 566 | 142 | 121 | 54.0 | 0.20 |
IL4 | rs2243270 | 659 | 4.3 | 577 | 160 | 133 | 54.6 | 0.11 |
Refined phenotypes | ||||||||
SLC22A5 | rs14701 | 462 | 6.1 | 385 | 101 | 87 | 53.7 | 0.31 |
IL13 | rs1800925 | 461 | 3.7 | 412 | 121 | 128 | 48.6 | 0.66 |
IL13 | rs1295686 | 461 | 2.9 | 423 | 139 | 130 | 51.7 | 0.58 |
IL13 | rs20541 | 473 | 2.2 | 442 | 139 | 138 | 50.2 | 0.95 |
IL4 | rs2243250 | 461 | 2.9 | 419 | 117 | 95 | 55.2 | 0.13 |
IL4 | rs2070874 | 461 | 5.3 | 393 | 107 | 83 | 56.3 | 0.08 |
IL4 | rs2243270 | 462 | 4.5 | 402 | 120 | 94 | 56.1 | 0.08 |
Cross-block haplotype rs20541(T)-rs2070874(T) |
362 | 0.0 | 362 | 64 | 44 | 59.3 | 0.05 |