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. Author manuscript; available in PMC: 2011 Jan 5.
Published in final edited form as: Thorax. 2009 Jan 8;64(4):345–352. doi: 10.1136/thx.2008.102111

Table 4.

Transmission disequilibrium test (TDT) for principal phenotypes and refined phenotypes

Gene SNP Families % failed Complete
families
Allele 2
transmitted
Allele 2
not transmitted
% transmission p Value
Principal phenotypes
SLC22A5 rs14701 658 5.6 554 139 129 51.9 0.54
IL13 rs1800925 659 4.1 582 162 177 47.8 0.42
IL13 rs1295686 660 3.3 598 197 177 52.7 0.30
IL13 rs20541 673 2.4 625 200 191 51.2 0.65
IL4 rs2243250 660 2.7 604 154 132 53.8 0.19
IL4 rs2070874 658 4.8 566 142 121 54.0 0.20
IL4 rs2243270 659 4.3 577 160 133 54.6 0.11
Refined phenotypes
SLC22A5 rs14701 462 6.1 385 101 87 53.7 0.31
IL13 rs1800925 461 3.7 412 121 128 48.6 0.66
IL13 rs1295686 461 2.9 423 139 130 51.7 0.58
IL13 rs20541 473 2.2 442 139 138 50.2 0.95
IL4 rs2243250 461 2.9 419 117 95 55.2 0.13
IL4 rs2070874 461 5.3 393 107 83 56.3 0.08
IL4 rs2243270 462 4.5 402 120 94 56.1 0.08
Cross-block haplotype
rs20541(T)-rs2070874(T)
362 0.0 362 64 44 59.3 0.05