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Classification of microscopic histopathological and morphogenetic changes that occur during N-nitrosomethylbenzylamine–induced esophageal tumorigenesis in the Fischer 344 rat esophagus. (A) Normal esophageal epithelium, (B) epithelial hyperplasia, (C) low-grade dysplasia, (D) high-grade dysplasia, (E) squamous cell papilloma, and (F) carcinoma in situ.
