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. Author manuscript; available in PMC: 2011 Jan 5.
Published in final edited form as: Nutr Cancer. 2006;54(1):33–46. doi: 10.1207/s15327914nc5401_5

Table 5.

Effects of Freeze-Dried STRWs and BRBs on NMBA-Induced Preneoplastic Lesions in the Rat Esophagusa

No. Lesions/Rat (mean ± SE)

Treatment Rats (n) Epithelial Hyperplasia Low-Grade Dysplasia High-Grade Dysplasia
Vehicle control 7 0 0 0
10% STRWs 15 0 0 0
NMBA control 12 43.3 ± 2.4 9.6 ± 2.4 11.6 ± 1.8
NMBA + 5% STRWs 14 40.6 ± 2.6 20.6 ± 3.5b 5.6 ± 0.9b
NMBA + 10% STRWs 15 33.5 ± 2.1b 19.3 ± 2.8b 4.1 ± 0.5b
Vehicle control 10 18.8 ± 2.4 2.0 ± 0.8 0
10% BRBs 10 20.8 ± 2.9 2.7 ± 1.0 0
NMBA control 15 44.7 ± 1.7 9.5 ± 0.8 7.2 ± 0.9
NMBA + 5% BRBs 15 40.6 ± 2.0 8.3 ± 0.9 4.1 ± 0.6b
NMBA + 10% BRBs 15 41.7 ± 2.8 8.7 ± 1.0 4.9 ± 0.8b
a

Abbreviations are as follows: STRWs, strawberries; BRBs, black raspberries; NMBA, N-nitrosomethylbenzylamine.

b

Statistically significant relative to NMBA controls (P < 0.05). STRW data are taken from Ref. 31 and BRB data are from Ref. 32.