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. Author manuscript; available in PMC: 2011 Jan 5.
Published in final edited form as: Reprod Biomed Online. 2009 Jul;19(1):79–88. doi: 10.1016/s1472-6483(10)60050-8

Figure 4.

Figure 4

Dihydrolipoamide dehydrogenase (DLD) enzymatic activity in oocytes and embryos. (a) Activity level in oocytes from wild-type and heterozygous females and from blastocysts of three different genotypes. The additional horizontal line in the box-whisker plots represents the means for the group, and groups that are statistically different (P < 0.05) are indicated with different letters. (b) Model for maternal-to-embryonic transition for DLD enzyme. The half-life of maternal DLD was estimated based on the loss of activity from the oocyte to the blastocyst in Dld-deficient embryos. Embryonic production of DLD enzyme was estimated by determining differences in enzyme activity in −/− and +/− or +/+ embryos, which reflects expression from one or two alleles, respectively.