Table 3.

Statistical analysis of relationship between prion protein deposition, tau phosphorylation and disease duration

Parameter 1	Parameter 2	Number of cases	R	Significance level
Tau (frontal cortex), no Aβ amyloid	PrP deposits: the strongest score was taken into account	28	0.69	<0.01
Tau (frontal cortex), no Aβ amyloid	Duration of illness	28	−0.037	n.s.
Tau (cerebellum), all prion diseases)	PrP deposits	69	0.50	<0.01
Tau (cerebellum), all prion diseases	Duration of illness	63	0.063	n.s.
Tau (cerebellum), sCJD only	PrP deposits	52	0.39	<0.01
Tau (cerebellum), sCJD only	Duration of illness	49	−0.16	n.s.

Parameters 1 and 2 were correlated in Pearson’s test (n.s. not significant)