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. Author manuscript; available in PMC: 2011 Dec 22.
Published in final edited form as: Tetrahedron Lett. 2010 Dec 22;51(51):6748–6752. doi: 10.1016/j.tetlet.2010.10.087

Table 9.

Vinylation attempts with 2-bromo-1,3,5-trimethoxybenzene (5)

Entrya Time 5:6:7b Yield of 6c
30 20 min 1:0:0 n/a
31 30 min 1:0:0 n/a
32 60 min 1:0:0 n/a
a

5 mol % PdCl2(dppf)CH2Cl2, THF:H2O (9:1) at 0.051 M, 3 equiv Cs2CO3, 150 °C.

b

Determined by 1H NMR integration of the crude mixture.

c

Isolated yield.