Figure 2).

Pro-oxidative/antioxidative effects in the myocardium of diabetic rats and in the hearts of normal rats preconditioned with one cycle of ischemia/reperfusion (I-PC) (5 min each). A Effects of acute diabetes mellitus (D) and I-PC on the tissue levels of antioxidants determined by high-performance liquid chromatography. α-toc alpha-tocopherol; CoQ9 Coenzyme Q9; CoQ10 Coenzyme Q10. Data are presented as mean ± SEM of eight to 10 hearts per group. *P<0.05 versus nondiabetic control (C) hearts. B Myocardial concentration of thiobarbituric acid reactive substances (TBARS) at baseline (BL) and after test ischemia (I) in the nonpreconditioned controls, hearts preconditioned with I-PC and hearts from one-week diabetic rats. Data are presented as mean ± SEM of six to eight hearts per group. *P<0.05 versus BL; †P<0.05 versus nondiabetic controls