FIGURE 11.

Comparative retinal function assessed by dark-adapted ERG b-wave measurement at 1 and 4 weeks after surgery. A, Overlaid representative waveforms from each treatment group at 1 week postoperatively in response to a bright flash stimulus (2.1 log cd-s/m²). A and S groups have slightly larger b-wave amplitudes than the C and M groups. The short-duration negative spike at 0.05 msec is an electrical implant spike from the A and M ASR devices. B, Overlaid representative waveforms from A, C, and M groups at 4 weeks postoperatively. The b-wave amplitude from the active implant A group is twice as large as from the C and M groups. C, Average (±SEM) a- and b-wave amplitudes at 1 week postoperatively from the A (n=12), C (n=9), M (n=7), and S (n=7) groups. At the brightest flash intensity, the b-wave amplitudes of the A and S groups are significantly greater than those of the M and S groups. No significant intergroup differences were observed in a-wave amplitudes. D, Average amplitude of a- and b-waves at 4 weeks postoperatively from the A (n=5), C (n=3), and M (n=4) groups. At most intensities, the average b-wave amplitude from the A group is significantly larger than the M and C groups. No significant differences in a-wave amplitudes were observed between the groups. Reprinted with permission from the Association for Research in Vision and Ophthalmology.⁷⁷