Table 1.
Effect of hrGal-1 on soluble mediators release
| Group/Treatment | TNF-α(pg/ml) | IL-1β(pg/ml) | IL-6 (pg/ml) |
|---|---|---|---|
| Control | ND | ND | ND |
| 4h/vehicle | 91.93 ± 13.5 | 374.4 ±44.38 | 668 ± 46.94 |
| 4h/ hrGal-1 | 30.07 ± 10.93* | 139.8 ±35.57* | 724.6 ± 20.13 |
| 24h/vehicle | ND | ND | ND |
| 24h/hrGal-1 | ND | ND | ND |
Mice pretreated intraperitoneally with vehicle (PBS) or hrGal-1 (0.3 μg) received 1mg of zymosan i.p. at time 0. Lavage fluid was collected at 0, 4 and 24h later, and serum concentrations of TNF-α, IL-1β, and IL-6 were determined. Results are from 6 mice per group. ND, not detected.
*
P < 0.05 versus corresponding vehicle group values.