Fig. 2.

Prediction of blood pressure (BP) status by CHGB promoter haplotypes in a population (of European ancestry) with BP extremes. Haplotypes (or haplotype pairs) are ordered by rank of association with elevated BP. Left: Haplotype (chromosome) effects. Right: Haplotype pair (diploid haplotype) effects. The two most common haplotypes (AA and CT) are more frequent in individuals with lower BP, whereas the two less common haplotypes (CA and AT) are more frequent in those with higher BP. CHGB—chromogranin B; HT—hypertensive; NT—normotensive. (Adapted from Zhang et al. [47•])