FIG. 1.
(A) The EAAT2 transcripts with long 5′ UTR are not constitutively translated but require extracellular factors to induce translational read-through. The 5′ UTR may form secondary structure, or stem-loops, which negatively affect translation by impeding the binding or migration of 40S ribosomal subunits. (B) A schematic illustration of the enzyme-linked immunosorbent assay procedures.