Table 4. Differentially regulated genes in the right ventricle of pulmonary trunk banded (PTB) rats versus chronic hypoxic rats.
Public ID | Encoded protein | Fold change | |
PTB | Hypoxia | ||
NM_024400 | A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1) | 0.60 | −0.61 |
BG671506 | avian sarcoma virus CT10 (v-crk) oncogene homolog | 0.38 | −0.41 |
AI454911 | endothelial monocyte activating polypeptide 2 | 0.15 | −0.28 |
BF282186 | eukaryotic initiation factor 5 (eIF-5) | 0.35 | −0.35 |
AI713966 | insulin-like growth factor binding protein 3 | 0.41 | −0.84 |
NM_012588 | insulin-like growth factor binding protein 3 | 0.33 | −0.78 |
NM_053713 | Kruppel-like factor 4 (gut) | 0.48 | −0.68 |
AA818911 | mob protein | 0.21 | −0.39 |
AI409862 | protein phosphatase 1, catalytic subunit, beta isoform | 0.22 | −0.37 |
NM_033096 | protein phosphatase 1B, magnesium dependent, beta isoform | 0.12 | −0.36 |
AY043246 | regulator of G-protein signaling protein 2 | 0.44 | −0.99 |
AI454052 | c-kit receptor tyrosine kinase | −0.24 | 0.91 |
AW914928 | DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 25 | −0.36 | 0.51 |
BI275583 | lectin, galactoside-binding, soluble, 2 (galectin 2) | −0.17 | 0.15 |
In addition 4 genes (LYRIC, glioma tumor suppressor candidate region gene 2, splicing factor (arginine/serine-rich 5), transducer of ERBB2 1, and TRAP-complex gamma subunit) were unaltered in PTB, but down-regulated in hypoxia, but with fold changes less than 0.5.