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. 2010 Dec 13;11:596. doi: 10.1186/1471-2105-11-596

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Copyright ©2010 Bebek et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Top three significant Apc petals. The top three petals, Apc-Hapln1 (left, p = 0.0068), Apc-Kras (middle, p = 0.0157), and Apc-Prkd1 (right, p = 0.0167), found to be significant after coexpression correlation with proteomic targets are shown. The darker nodes represent CAN-gene proteins. When searching for paths, CAN-genes were not differentiated from other proteins on the network, hence multiple CAN-genes exist in some of the petals. The dashed edges represent novel interactions predicted to exist on the network, whereas solid edges are known interactions.