Table 1.
ET-1 Risk Group (fmol/ml) | |||
---|---|---|---|
Variable | Total Cohort (N=101) | Low (N=76) (0.12-1.15) | High (N=25) (1.16–5.14) |
Age, mean (SD), years | 67.0 (9.0) | 66.4 (8.7) | 69.2 (10.2) |
Female | 3.1% | 2.6% | 6.0% |
Non White Race | 8.8% | 9.0% | 8.0% |
History of Hypertension | 85% | 83% | 94% |
Active smokers | 14.3% | 14.0% | 14.6% |
LVEF, mean (SD) | 52.7 (9.6) | 54 (8.6) | 46.2 (11.2) |
Obesity (BMI >30) | 46.8% | 49% | 37% |
Diabetes | 30% | 29% | 32% |
Mean BDI Score (SD) | 8.1 (5.9) | 7.44 (5.20) | 10.77 (7.95) |
Medications | |||
Ace inhibitors | 52% | 48% | 63% |
Beta-Blockers | 77% | 78% | 77% |
Aspirin | 67% | 68% | 63% |
Calcium Channel Blocker | 31% | 30% | 32% |
Statins | 89% | 89% | 89% |
ET-1 = Endothelin-1
fm/ml = fentomole/milliliter
LVEF = left ventricular ejection fraction
BMI = body mass index
BDI = Beck Depression Inventory