Table 3.
Demographic, fasting lipid profile and PON1 status of healthy controls and patients with liver diseases
Healthy controls (n=53) | Acute viral hepatitis (n=14) | Cirrhosis with portal hypertension (n=33) | Leptospirosis (n=14) | Sepsis (n=15) | Left ventricular failure (n=9) | Falciparum malaria (n=10) | |
Age (years) | 34±12 | 47±11 | 39±9 | 39±6 | 35±8 | 36±11 | 34±7 |
Sex (M/F) | 31/22 | 9/5 | 19/14 | 6/8 | 11/4 | 6/3 | 6/4 |
TC (mg/dL) | 154.5±16.27 | 137±72.57 | 97.65±56.63** | 124.41±49.75 | 143.54±91.66 | 78.15±30.9* | 101.14±13.71 |
HDLC (mg/dL) | 50.14±4.21 | 68.5±75.7 | 11.27±13.66** | 6.6±5.06** | 23.16±13.6* | 4.8±1.7** | 7.84±6.21** |
TAG (mg/dL) | 70.02±13.23 | 130.13±130 | 97.13±91.6 | 176.34±87** | 136.61±63.67 | 130.52±86.2 | 318.37±126.59** |
LDLC (mg/dL) | 90.8±14.57 | 124.5±90.24 | 80.33±61.98 | 76.44±32.29 | 135.53±121.7 | 64.65±24.47 | 74.35±21.86 |
RATIO (mg/dL) | 3.07±0.38 | 5.06±4.29 | 10.59±6.34** | 8.44±4.52** | 9.46±2.74** | 9.8±3.17** | 6.32±2.07 |
PON1 (mg/dL) | 141.97±8.27 | 58.6±22.34** | 126.47±104.87 | 86.8±32.43 | 53.76±25.81** | 134.45±102 | 76.16±27.83* |
P<0.001 compared to normal controls
P<0.05 compared to normal controls; Data expressed as mean±SD