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. 2001 Feb 20;98(5):2497–2502. doi: 10.1073/pnas.051611498

Table 1.

Estimates (± standard errors) of divergence times (MY) between mice and rats and between humans and rodents

Method Mouse-rat (t1)
Human-rodent (t2)
PC PC Gamma PC PC Gamma
IP approach

44.0  ± 3.4 38.5  ± 3.2 113.4  ± 5.0 102.9  ± 5.0
CD approach

d1 (ā = 0.76) 40.7  ± 3.0 34.4  ± 2.8 112.3  ± 5.4 99.9  ± 5.3
d2 (ā = 0.76) 39.1  ± 2.3 33.0  ± 2.0 110.0  ± 4.4 97.6  ± 4.4
d3 (a = 0.57) 32.9  ± 2.3 95.5  ± 4.2
d3 (a = 0.28) (25.2  ± 2.0)  (82.0  ± 4.0) 
dL (a = 0.5) 32.0  ± 5.0 90.0  ± 10.0

d1, unweighted average distance; d2, average distance weighted with sequence length; d3, multiprotein gamma distance; dL, Lynch's distance. The standard errors for the CD approach were computed by the jackknife method. The standard errors of t̂1 and t̂2 obtained by using Eq. 5 for d3 with a = 0.57 were 2.0 and 4.0, respectively.