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. Author manuscript; available in PMC: 2011 Jan 6.
Published in final edited form as: Pharm Res. 2010 May 19;28(1):41–57. doi: 10.1007/s11095-010-0169-8

Fig. 10.

Fig. 10

(i) Scanning electron micrographs of model 7 MN following application of a compression force of 0.02 N per needle (A), model 6 MN following application of a force of approximately 0.17 N perpendicular to the MN shaft (B), model 1 MN following application of a force of approximately 0.08 N perpendicular to the MN shaft (C) (ii) Illustrative digital images of holes created in neonatal porcine skin using various insertion forces for Model 1 MN arrays. A: 0.44 N per needle, B: 0.11 N per needle, C: 0.03 N per needle, D: 0.01 N per needle, E: 0.0056 N per needle. (iii) Illustrative digital image of Gantrez® AN-139 MN arrays (model 3) showing slight elongation in MN tips (due to initiation of dissolution in interstitial tissue fluid) following insertion into neonatal porcine skin for 30 s.