| First generation |
|
|
| Albunex |
5% human albumin with stabilized microbubbles |
Mallinckrodt |
| Echovist (SHU 454) |
Standardized microbubbles with galactose shell |
Schering |
| Levovist (SHU 508) |
Stabilized, standardized microbubbles with galactose, 0.1% palmitic acid shell |
Schering |
| Myomap |
Albumin shell |
Quadrant |
| Quantison |
Albumin shell |
Quadrant |
| Sonavist |
Cyanoacrylate shell |
Schering |
| Sonazoid |
C4F10 with lipid stabilizer shell |
GE healthcare |
| Second generation |
| Definity/luminity |
C3F8 with lipid stabilizer shell |
Bristol–myers squibb medical imaging |
| Imagent-imavist |
C6H14 with lipid stabilizer shell |
Alliance |
| Optison |
C3F8 with denatured human albumin shell |
GE healthcare |
| Bisphere/cardiosphere |
Polylactide-coglycolide shell with albumin overcoat |
- |
| SonoVue (BR1, Bracco, Italy) |
SF6 gas with lipid stabilizer shell |
Bracco |
| AI700/imagify |
C4F10 gas core stabilized with polymer shell |
Acusphere |
| Third generation |
| Echogen |
Dodecafluoropentane (DDFP) liquid in phase shift colloid emulsion |
Sonus pharmaceuticals |
