Table 1.
Differentially expressed genes in PEITC-treated rat esophagus associated with oxidative reductase activity and protein metabolism
| Unigene | Reporter name | Gene symbol | Sequence description | NCBI gene ID | Accession | PEITC vs control, fold change |
|---|---|---|---|---|---|---|
| Thioredoxin-related genes | ||||||
| Rn.29777 | A_44_P559392 | Txn | Thioredoxin | 3197112 | BM389527 | 1.972 |
| Rn.44920 | A_44_P258855 | Qscn6 | Quiescin Q6 | 3206319 | NM_053431 | 1.807 |
| Rn.67581 | A_44_P554454 | Txnrd1 | Thioredoxin reductase 1 | 3207283 | NM_031614 | 1.537 |
| Protein metabolism–related genes | ||||||
| Rn.107819 | A_44_P170541 | Ptpre | Protein tyrosine phosphatase, receptor type, E | 114767 | XM_341950 | 8.03 |
| Rn.3841 | A_44_P537780 | Hsp27 | Heat shock 27 kDa protein | 24471 | BG375996 | 2.05 |
| Rn.94551 | A_44_P242664 | Psmb3 | Proteasome (prosome, macropain) subunit, β type, 3 | 29676 | AA859484 | 1.53 |
| Rn.119867 | A_44_P261874 | Hspca | Heat shock protein 1, α | 299331 | NM_175761 | −1.51 |
| Rn.55145 | A_44_P477785 | Eef2 | Eukaryotic translation elongation factor 2 | 29565 | NM_017245 | −1.52 |
| Rn.97889 | A_44_P262192 | Cct4 | Rattus norvegicus chaperonin subunit 4 (δ; Cct4) | 29374 | NM_182814 | −1.54 |
| Rn.10958 | A_44_P517591 | Eef2k | Eukaryotic elongation factor 2 kinase | 25435 | NM_012947 | −1.54 |
| Rn.92980 | A_44_P605733 | Rpl5 | Ribosomal protein L5 | 81763 | NM_031099 | −1.55 |
| Rn.12223 | A_44_P230712 | Rasa1 | RAS p21 protein activator | 25676 | NM_013135 | −1.56 |
| Rn.89756 | A_44_P1039856 | Rock1 | Rho-associated kinase β | 81762 | NM_031098 | −1.58 |
| Rn.6822 | A_44_P160550 | Capn2 | Calpain 2 | 29154 | NM_017116 | −1.61 |
| Rn.107726 | A_44_P355947 | Rpl3 | Ribosomal protein L3, mRNA (NM_198753) | 300079 | NM_198753 | −1.64 |
| Rn.90191 | A_44_P259979 | Jak1 | Similar to tyrosine-protein kinase JAK1 | 84598 | XM_342872 | −1.71 |
| Rn.93345 | A_44_P254283 | Map4k3 | Mitogen-activated protein kinase kinase kinase kinase 3 | 170920 | XM_343006 | −1.84 |
| Rn.88642 | A_44_P101644 | Rock2 | RhoA-binding serine/threosine kinase α (ROKα) | 25537 | NM_013022 | −2.06 |
| Rn.7687 | A_44_P1006977 | Lars | Rattus norvegicus leucyl-tRNA synthetase | 291624 | NM_001009637 | −2.10 |
| Rn.10484 | A_44_P111897 | Map2 | Microtubule-associated protein 2 | 25595 | NM_013066 | −5.69 |
Abbreviation: NCBI, National Center for Biotechnology Information.