Table 3.
Biological processes in NMBA-treated rat esophagus that were modulated by PEITC treatment
| Gene Ontology biological process | No. genes | P |
|---|---|---|
| Cell cycle | 30 | 0.000103 |
| Cell proliferation | 36 | 0.000114 |
| Cell death | 22 | 0.000343 |
| Response to stress | 34 | 0.000637 |
| Apoptosis | 20 | 0.001004 |
| Lipid metabolism | 24 | 0.005953 |
| Response to chemical substance | 10 | 0.010004 |
| Mitotic cell cycle | 8 | 0.010651 |
| Induction of apoptosis | 12 | 0.012446 |
| Nuclear division | 7 | 0.013056 |
| Response to wounding | 15 | 0.014014 |
| Response to DNA damage stimulus | 8 | 0.020254 |
| Positive regulation of apoptosis | 12 | 0.023231 |
| Amino acid and derivative metabolism | 13 | 0.027037 |
| Amine metabolism | 13 | 0.028625 |
| Glutathione metabolism | 4 | 0.029496 |
| Response to endogenous stimulus | 8 | 0.031913 |
| Carboxylic acid metabolism | 17 | 0.031929 |
| Organic acid metabolism | 17 | 0.031929 |
| Response to abiotic stimulus | 12 | 0.037509 |
| Protein localization | 17 | 0.039672 |
| One-carbon compound metabolism | 4 | 0.043354 |
| Translational initiation | 5 | 0.048176 |
NOTE: Genes were categorized per the Gene Ontology Consortium designations. The count column indicates the number of genes from the set of 1323 genes derived by statistical analysis that are associated with the specified category.