. Author manuscript; available in PMC: 2011 May 1.

Published in final edited form as: J Mol Cell Cardiol. 2009 Dec 31;48(5):979–988. doi: 10.1016/j.yjmcc.2009.11.018

Table 1.

Cardiac Mass

Genotype	n	BW (g)	LV (mg)	LV/BW (mg/g)
Non-Tg	22	23.9 ± 0.7	76.6 ± 2.7	3.21 ± 0.07
β-Tg	22	24.8 ± 0.6	83.1 ± 2.4	3.37 ± 0.07
α-R92Q	12	25.5 ± 1.8	73.7 ± 10.1	2.93 ± 0.21^#
β-R92Q	12	23.9 ± 0.7	58.9 ± 2.3^**^##⁺	2.47 ± 0.06^**^##⁺
α-R92L	11	25.5 ± 0.9	69.6 ± 2.3	2.75 ± 0.08^*^##
β-R92L	11	23.4 ± 0.7	63.8 ± 2.4^*^##	2.73 ± 0.09^**^##

P<0.05,

^**

P<0.01 vs Non-Tg;

P<0.05,

^##

P<0.01 vs β-Tg;

⁺

P<0.05 vs α-R92Q

Body weight (BW), left ventricular weight (LV) and LV/BW for non-transgenic mice (Non-Tg), for mice with cardiac α-MyHC replaced with β-MyHC (β-Tg) and mice bearing either the R92L or R92Q mutation in cTnT with either predominately α- or β-MyHC. Replacing α-MyHC with β-MyHC in hearts with normal cTnT did not change these morphologic parameters. LV/BW were lower for mouse hearts bearing the R92Q and R92L cTnT mutations with normal α-MyHC; both LV and LV/BW were lower when α-MyHC was replaced with β-MyHC. The same results are obtained when the LV weights are normalized to tibia lengths (not shown). Means ± SEM.