Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jan 1;22(1):153–164. doi: 10.1091/mbc.E10-08-0732

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 Helmstaedt et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,“ “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology.

PMC Copyright notice

FIGURE 1: — Split Cand1 in A. nidulans and relatives. (A) candA-N (orange) and candA-C (yellow) genomic locus, mRNA, and protein. CandA-C carries NLS (RKRRR) at position 197–201. (B) Cand1/A alignments determined by Clustal W. Amino acid (aa) numbers represent protein lengths. Fungi with conserved Cand1/A NLS are indicated. A1-B2 HEAT repeats block Cul1 neddylation; β-hairpin and B25 impair Skp1 adaptor binding. (C) Expression of CandA-C (AGB266) during vegetative growth and early development. Western analysis of 60 μg of A. nidulans crude extract with functional candA-C::gfp (AGB266) or as control wild-type A4 (wt). Indicated sizes: CandA-C-GFP, 140 kDa; GFP, 27 kDa.