Figure 4.
Bat, the transcription regulator of the purple membrane regulon. (a) Positions and amino acids within the redox-responsive PAS (shaded orange)/PAC (shaded blue) domain, the photoresponsive GAF domain (purple font), and the HTH DNA binding motif (green font) are shown. The amino acids altered within the PAC domain in S9 Bat are indicated with a red font. (b) The double-frameshift mutation in the S9 bat gene. Deletion of a “G” (red font) and an insertion of an “A” (blue font) four codons apart has resulted in an altered amino acid sequence (shown below and above the aligned DNA sequences). The amino acid corresponding to the N85C mutation in the E. coli Aer protein is shaded in black (27).