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. 2011 Jan 6;6(1):e15861. doi: 10.1371/journal.pone.0015861

Figure 4. Influence of PRO 2000 co-administration on the type of T helper cell response.

Figure 4

The serum specific IgG1- and IgG2a titres were determined as indicators of a Th2 or Th1 type of response, respectively. (A) Serum IgG1/IgG2a endpoint titre ratios of vaginally immunized mice (described in Figure 3A–C). (B–D) BALB/c mice (n = 7) were primed s.c. with gp140 +/− PRO 2000 in FCA and were boosted using the same route and formulation without FCA. (B) Serum IgG1 endpoint titres; (C) IgG2a endpoint titres; (D) IgG1/IgG2a endpoint titre ratio. gp + PRO, combination of gp140 and PRO 2000. * p<0.05; ** p<0.01.