Table 3. Overview of antivirals mutations virus isolates from avian hosts (NCBI).
| NA subtype | Mutation 1) | Type of residue 2) | No. |
| N1 | (o) I117V; (z) E119G/A/D | F; F | 1 |
| (o) I117V | F | 36 | |
| (z) R118K | C | 1 | |
| (o) E119V | F | 1 | |
| (z) E119G/A/D | F | 2 | |
| (o) I222V | F | 5 | |
| (o) H274Y | F | 4 | |
| (o) R292K | C | 2 | |
| (o) N294S | F | 4 | |
| (z) S/R371K | C | 1 | |
| All | 57 | ||
| N2 | (z) R118K; (z) R152K; (o) D198N | C; C; F | 1 |
| (z) V116A | F | 1 | |
| (z) E119G/A/D | F | 5 | |
| (z) R152K | C | 2 | |
| (z) D198N | F | 1 | |
| (o) I222V | F | 1 | |
| (z) R224K | C | 2 | |
| (z) H274Y | F | 1 | |
| (o) N294S | F | 1 | |
| (o) I314V | 40 | ||
| All | 55 | ||
| N3 | (z) V116A | F | 1 |
| (o) I222V | F | 5 | |
| (o) L/I314V | 3 | ||
| All | 9 | ||
| N5 | (o) D198N | F | 7 |
| All | 7 | ||
| N6 | (o) I222V | F | 2 |
| All | 2 | ||
| N8 | (z) V116A | F | 1 |
| (o) I117V | F | 1 | |
| All | 2 | ||
| Total | 132 |
1)
(z) - zanamivir related mutations; (o) - OC related mutation.
2)
C - catalytic residue; F - framework residue.