Table 1.
Comparison of ECG parameters in Kcnq1+/+ and Kcnq1−/− mice
| Parameters | Kcnq1+/+ | Kcnq1−/− | P-value |
|---|---|---|---|
| RR, ms | 132 ± 18 | 128 ± 18 | 0.5 |
| Pamp, mV × 10−2 | 21 ± 5 | 29 ± 8 | <0.001 |
| P-wave duration, ms | 12 ± 1 | 13 ± 2 | 0.03 |
| P-wave area (V*ms × 10−1) | 13 ± 3 | 19 ± 6 | <0.001 |
| PR, ms | 37 ± 5 | 41 ± 4 | 0.016 |
| QRS duration, ms | 9 ± 1 | 10 ± 2 | 0.016 |
| QRS amplitude (mV × 10−2) | 148 ± 39 | 236 ± 65 | <0.001 |
| JT, ms | 60 ± 11 | 71 ± 11 | 0.006 |
| QT, ms | 69 ± 11 | 82 ± 11 | 0.003 |
| QTc, ms | 61 ± 11 | 72 ± 5 | <0.001 |
| T-wave area (V*ms × 10−1) | 71 ± 24 | 141 ± 55 | <0.001 |
All data are presented as mean ± SD. Sample sets of 16 were used for both Kcnq1−/− and Kcnq1+/+ mice. Data sets were compiled by using Student's t test.