Table 1.
The signature of 25 genes in the network classification model. Enrichment shows that there are 23 unique genes in the signature.
| Gene symbol | Gene title | Cytoband | Pathway |
|---|---|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 17q22 | ABC transporters |
| BICD2 | bicaudal D homolog 2 (Drosophila) | 9q22.31 | |
| CDA | cytidine deaminase | 1p36.2-p35 | Pyrimidine metabolism, Drug metabolism |
| CLDN3 | claudin 3 | 7q11.23 | Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration |
| DPP4 | dipeptidyl-peptidase 4 | 2q24.3 | |
| HGD | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 3q13.33 | Tyrosine metabolism, Styrene degradation |
| ITPKA | inositol 1,4,5-trisphosphate 3- kinase A | 15q14-q21 | Inositol phosphate metabolism, Calcium signaling pathway, Phosphatidylinositol signaling system |
| KRT14 | keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) | 17q12-q21 | Cell communication |
| KRT6A, KRT6B, KRT6C | keratin 6A, keratin 6B, keratin 6C, | 12q12-q13 | Cell communication |
| MUC3B | mucin 3B, cell surface associated | 7q22 | |
| MUC5B | mucin 5B, oligomeric mucus/gel- forming | 11p15.5 | |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 1q25 | Nicotinate and nicotinamide metabolism |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | MAPK signaling pathway |
| RHCG | Rh family, C glycoprotein | 15q25 | |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 | 18q21.3-q22 | |
| SOX2 | SRY (sex determining region Y)- box 2 | 3q26.3-q27 | |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 5q32 | |
| SPRR1A | small proline-rich protein 1A | 1q21-q22 | |
| TJP3 | tight junction protein 3 (zona occludens 3) | 19p13.3 | Tight junction |
| TOX3 | TOX high mobility group box family member 3 | 16q12.1 | |
| VSNL1 | visinin-like 1 | 2p24.3 |