Skip to main content
. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Chem Res Toxicol. 2010 Sep 28;23(10):1601–1607. doi: 10.1021/tx100190k

Fig. 4.

Fig. 4

(S)-HNE enantiomer significantly affects the redox status in cultured hepatocytes. Flow cytometric analysis of cellular pyridine nucleotide redox status was performed as described in “Experimental Procedures”. NAD(P)H levels, used as an indicator of intracellular redox status, were 2-fold lower in (S)-HNE treated cells 24 hours after exposure, relative to racemic and (R)-HNE. Results are representative of three independent experiments. Statistical analysis was performed using Prism. * p < 0.01