Figure 1. Immunohistochemical staining for KSHV LANA shows significant heterogeneity among different patients.
A and B: a representative biopsy with a scant number of LANA-positive spindle cells. C and D: a biopsy from another patient with a moderate amount of LANA positivity. E and F: numerous LANA positive cells in a biopsy that showed a nodule with a dense concentration of spindle cells. (A,C,E: LANA, 2 × magnification; B,D,F: LANA, 20 × magnification).