Table 2.
Comparison of Gynecological History of Women with Chronic Fatigue Syndrome and Nonfatigued Controls
| Study group | CFS (n = 36) | Controls (n = 48) | OR (95% CI) | p |
|---|---|---|---|---|
| Gynecological variable | ||||
| Age at menarchea | 12.3 ± 0.2 | 12.4 ± 0.2 | ND | 0.63 |
| Duration of menstrual period (n = 23)b | 5.4 ± 0.4 | 5.0 ± 0.5 | ND | 0.55 |
| Bleeding between periodsc | ND | 1.0 | ||
| Yes | 1 (9.1) | 1 (7.7) | ||
| No (n = 24)d | 10 (90.9) | 12 (92.3) | ||
| Amenorrheac | ||||
| Yes | 21 (53.9) | 18 (46.2) | 2.33 (0.88-6.23) | 0.06 |
| No | 15 (46.1) | 30 (53.8) | Reference | |
| Number of pregnancies/womana | 2.8 ± 0.3 | 2.0 ± 0.2 | ND | 0.05 |
| History of pelvic painc | ||||
| Yes | 8 (22.2) | 1 (1.7) | 13.43 (1.61-608.2) | 0.004 |
| No | 28 (77.8) | 47 (98.3) | Reference | |
| History of endometriosisc | ||||
| Yes | 13 (36.1) | 8 (16.7) | 2.83 (1.02-7.83) | 0.046 |
| No | 23 (63.8) | 40 (83.3) | reference | |
| Other gynecological conditionsc | ||||
| Yes | 12 (33.3) | 8 (16.7) | 2.50 (0.80-7.93) | 0.078 |
| No | 24 (66.7) | 40 (83.3) | reference | |
| Any gynecological surgeryc | ||||
| Yes | 28 (77.8) | 26 (54.2) | 2.96 (1.02-8.79) | 0.045 |
| No | 8 (22.2) | 22 (45.8) | Reference | |
| Number of gynecological surgeries per persona | 1.75 ± 0.29 | 1.08 ± 0.20 | ND | 0.05 |
| History of other gynecological surgeryc,e | ||||
| Yes | 16 (44.4) | 12 (25.0) | 2.40 (0.86-6.75) | 0.06 |
| No | 20 (55.6) | 36 (75.0) | ||
| Menopausal womenc | 25 (69.4) | 35 (72.9) | ||
| Mean agea | 55.6 ± 1.0 | 54.9 ± 1.1 | ND | 0.65 |
| Age at menopause (years)a | 41.7 ± 2.3 (n = 20) | 46.1 ± 1.5 (n = 28) | ND | 0.11 |
| Age at natural menopause | 50.3 ± 1.5 (n = 6) | 49.2 ± 1.6 (n = 16) | ND | 0.68 |
| Age at surgical menopause | 31.9 ± 2.4 (n = 14) | 38 ± 2.7 (n = 12) | ND | 0.29 |
| Duration of reproductive perioda | 29.4 ± 2.2 (n = 20) | 33.4 ± 1.5 (n = 28) | ND | 0.13 |
| Hysterectomyc | ||||
| Yes | 19 (76) | 19 (54.3) | 2.67 (0.76-9.72) | 0.09 |
| No | 6 (24) | 16 (45.7) | Reference | |
| Oophorectomyc | ||||
| Yes | 14 (56) | 12 (34.3) | 2.44 (0.75-8.06) | 0.11 |
| No | 11 (44) | 23 (65.7) | Reference |
a
Mean ± SEM.
b
11 women with CFS and 12 controls.
c
n (%).
d
11 women with CFS and 13 controls.
e
Includes dilation and curettage (D&C), cesarean-sections, tubal ligations, and other.
CI, confidence interval; ND, net done; OR, odds ratio.