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. 2010 Sep 28;19(1):181–187. doi: 10.1038/mt.2010.208

Figure 4.

Figure 4

Preservation of elastic fibers by chimeric R-ODN without suppression of macrophage accumulation. (a) Histological sections of rat aorta stained with EVG stain at 4 weeks after transfection, and percentage of area positive for elastic fibers (n = 6). (b) Immunohistochemical staining of macrophages at 1 week after operation. The bars represent mean ± SEM. *P < 0.05 versus sham and chimeric R-ODN analyzed by Tukey–Kramer test. Bar in a upper panels = 1,000 µm; lower panels = 200 µm; in b = 200 µm. chimera, AAA model transfected with chimeric R-ODN; control, AAA model treated with saline; EVG, elastic van Gieson's; PS-ODN, phosphorothioate linear-type decoy oligodeoxynucleotide; R-ODN, ribbon-type decoy oligodeoxynucleotide; scrambled, AAA model transfected with scrambled R-ODN.