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. 2010 Oct 19;19(1):150–158. doi: 10.1038/mt.2010.225

Figure 6.

Figure 6

Effects of MyD88 signaling on tumor infiltration following VSV treatment. C57BL/6 or MyD88−/− mice (n = 3/group) bearing B16ova tumors were injected intratumorally with 5 × 108 pfu of HI-VSV (open columns) or VSV (filled columns). Draining lymph nodes were harvested 48 hours after VSV injection and analyzed by flow cytometry for (a) CD11b−GR1+B220+ or (b) CD11b+GR1+ cells. (c) Tumors harvested 24 hours following injection were analyzed for neutrophils (CD45+CD11b+GR1+F4/80−). HI, heat-inactivated; ns, nonsignificant; MyD88, myeloid differentiation primary response gene 88; pfu, plaque-forming unit; VSV, vesicular stomatitis virus.