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CdhR negatively regulates expression of luxS (A) and mfa (B). mRNA levels in P. gingivalis wild type (WT), ΔcdhR and CΔcdhR strains were measured by quantitative RT-PCR. Fold difference is expressed mRNA levels after contact with S. gordonii (Sg) or S. cristatus (Sc) relative to P. gingivalis alone. ND is no difference. Data are means with standard deviation of 3 independent experiments performed in duplicate. Asterisk denotes a significant difference at P < 0.01 (t test).
