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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Mol Microbiol. 2010 Oct 26;78(6):1510–1522. doi: 10.1111/j.1365-2958.2010.07420.x

Fig. 8.

Fig. 8

Model of circuitry governing heterotypic community formation between P. gingivalis and S. gordonii. P. gingivalis expressing Mfa and LuxS can bind and accumulate on a substratum of S. gordonii. Communication between S. gordonii and P. gingivalis requires Mfa and is transduced through Ltp1 indirectly to CdhR. Higher levels of CdhR decrease the amount of Mfa and LuxS and consequently restrain P. gingivalis accumulation. Loss of AI-2 will further increase cdhR expression which may compensate for loss of signal due to the reduction of the Mfa fimbriae.