Table 1.
Group | Control | Heroin | Heroin-cocaine | Cocaine |
---|---|---|---|---|
Number | N = 7 | N = 8 | N = 7 | N = 7 |
Age (yr) | 46 ± 8 | 41 ± 10 | 45 ± 7 | 45 ± 9 |
Race B/W | 3/4 | 4/4 | 3/4 | 5/2 |
Gender | M = 7, F = 0 | M = 7, F = 1 | M = 5, F = 2 | M = 6, F = 1 |
Storage time (days) | 1066 ± 241 | 1136 ± 164 | 1155 ± 222 | 1004 ± 346 |
Brain pH | 6.78 ± 0.17 | 6.54 ± 0.16 | 6.64 ± 0.27 | 6.51 ± 0.36 |
Ethanol (blood) | n = 4 | n = 3 | n = 2 | n = 0 |
Morphine (μg/ml blood) | 0 | 0.35 ± 0.52 | 0.01 ± 0.02 | 0 |
6-MAM (μg/ml blood) | 0 | 0.011 ± 0.012 | 0.013 ± 0.033 | 0 |
Cocaine (μg/ml blood) | 0 | 0 | 0.04 ± 0.08 | 0.23 ± 0.30 |
Benzo. (μg/ml blood) | 0 | 0 | 0.32 ± 0.40 | 1.87 ± 2.00 |
Cause of death | ASCVD (n = 4), GSW (n= 1), stab wound (n = 1), drowning (n= 1). | Heroin intoxication/abuse (n = 7) cardiomyopathy (n= 1) | Heroin and cocaine intoxication/abuse (n =7) | Cocaine intoxication/abuse (n = 4) GSW (n = 1), ASCVD (n = 1), acute myocardial infarction (n= 1) |
Values presented as mean ± SD. ASCVD, atherosclerotic cardiovascular disease; Benzo, benzoylecgonine; B, Black; C, Caucasian; F, female; GSW, gun shot wound; M, male; 6-MAM, 6-Monoacetylmorphine; yr, year. Subjects are grouped based on their history of drug abuse and positive blood levels of the drug(s) at the time of death (see Supplemental Information).