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. Author manuscript; available in PMC: 2011 Jan 7.
Published in final edited form as: Cell. 2009 Dec 11;139(6):1157–1169. doi: 10.1016/j.cell.2009.11.014

Figure 2.

Figure 2

Reduced IGF signaling reduces Aβ associated neuroinflamation. A – H. Immuno histochemistry using GFAP antibody indicated reduced astrocytosis in brain sections of 12–13 month old AD;Igf1r+/− mice (D and H) compared to age matched AD mice (C and G). I. Image analysis confirmed the significance of the GFAP signal difference (six mice per genotype and 3 sections per animal were analyzed, P<0.05).