Table 1.
Characteristics of the generated species-specific PPI networks.
| species | #proteins | #PPIs | GO terms/protein | median PPI/protein |
|---|---|---|---|---|
| R. norvegicus (rno) | 973 | 1221 | 8 | 1 |
| M. musculus (mmu) | 3892 | 4670 | 4 | 1 |
| H. sapiens (hsa) | 13494 | 43637 | 2 | 2 |
| D. melanogaster (dme) | 10646 | 38723 | 3 | 3 |
| C. elegans (cel) | 3499 | 5858 | 1 | 1 |
| S. cerevisiae (sce) | 6578 | 67059 | 4 | 7 |
PPI networks for each species are created by integrating PPI data from DIP, BIND, IntAct, BioGrid, MIPS-MPPI, MINT and HPRD. Proteins within the networks are additionally associated with sequences, protein domains and GO annotations. For each species the number of proteins and protein interactions as well as the median number of GO terms per protein is specified.