Figure 4.
Imaging the cone mosaic in albinism. Shown are images of the cone mosaic centered at approximately 1 degree superior retina. The foveal center is located just off the bottom edge of each image. Images from a normal retina (A) and a subject with OCA1B (B) reveal a gradual decrease in cone packing density moving from bottom (inferior retina) to top (superior retina). Image from a subject with OA1 (C) reveals more uniform cone packing density. Cones vary individually in their reflectivity, and there are regional differences in image intensity, but this is in stark contrast to the pigment mottling seen in (D). Scale bar is 100 microns.